WHY VITAMIN E FROM TOCOTRIENOLS RATHER THAN TOCOPHEROLS?

Recent research has shown that alpha tocopherol above 15% can interfere with the benefits of tocotrienol both directly (Ref 1-6) and indirectly (Ref 1, 4, 7-11) and for these reasons we have opted to supply this pure product that contains no tocopherols at all. In addition studies have shown delta tocotrienol to be the most potent antioxidant of the 8 vitamin E series, followed by gamma tocotrienol. Studies on the benefits of tocotrienols demonstrate an average dosage of 200mg or more per day to be optimal. 

TOP 10 HEALTH BENEFITS OF ANNATTO TOCOTRIENOLS
 

1. Increase Life Expectancy in Cancer Patients

Tocotrienols have been studied in human cancer clinical trials and were shown to almost double overall life expectancy when taken with standard therapy. Tocotrienols have also repeatedly been shown to hinder the rapid multiplying of cancer cells.

2. Support Cardiovascular Health

Tocotrienols support healthy blood lipid levels and a healthy inflammatory response. They have been shown to simultaneously lower cholesterol, triglycerides and inflammation.

3. Improve Bone Health

Tocotrienols have been studied in a human clinical trial of post-menopausal osteopenia subjects and demonstrated that they help to resist bone loss.

4, Reduce Fat in the Liver

In a trial conducted with patients who had NAFLD (nonalcoholic fatty liver disease, suffered by 25% of the US population), tocotrienols were found to reduce both fat and enzymes in the liver as well as reduce inflammation of the liver. Those in the study saw an average weight loss of ~10lbs.

5. Promote Cell Health

The average human body has over 37 trillion cells. Each of those cells has a cell membrane that can be damaged without antioxidant protection. Tocotrienols’ antioxidant properties have been shown to be highly effective in preventing cells from going rancid and maintaining a strong cell wall.

6. Keep Inflammation at Bay

Tocotrienols’ proven ability to reduce inflammation can help prevent many associated diseases and chronic conditions, improving your overall health.

7. Uphold a Healthy Blood Sugar Level

Owing to their positive effect on lipids, tocotrienols may be beneficial for patients who need help managing blood sugar and insulin levels. They have been shown to improve insulin sensitivity and help the body create and process glucose better.

8. Boost Brain Health

Tocotrienols, in addition to a healthy lifestyle, may help keep you sharp and contribute to better brain health. Population-based studies conducted by the Karolinska Institute showed that higher levels of vitamin E tocopherols and tocotrienols in elderly subjects were associated with a lower risk of cognitive impairment and Alzheimer’s disease.

9. Reverse Skin Damage

Tocotrienols have been found to reduce hyperpigmentation, repair skin damage, heal wounds, protect from light exposure and suppress skin cancer.

10. Provide Radiation Protection

Tocotrienols help protect sensitive cells from destructive ionizing radiation.

Contents

Each capsule contains: Tocotrienols 125 mg of which: Delta Tocotrienols 90%, Gamma Tocotrienols 10% (From Annatto)

Other ingredients:

Bovine Gelatin, Glycerin, Purified Water.

Suggested Usage

Recommended dose 1 capsule 2-3 times daily with food.
The stated recommended dose can be changed as directed by your healthcare practitioner.
Do not exceed the recommended dose.
Consume within 3 months of opening.

Warnings

If pregnant or breast feeding, consult your health care practitioner before using.
Not suitable for vegetarians (due to gelatin capsule)
This product should not be used as a substitute for a varied diet. 
Store in a cool, dry place out of reach of children.

References

1. Qureshi, A.A., et al., Dietary alpha-tocopherol attenuates the impact of gamma-tocotrienol on hepatic3-hydroxy-3-methylglutaryl coenzyme A reductase activity in chickens. J Nutr, 1996. 126(2): p. 389-94.

2. Guthrie, N., et al., Inhibition of proliferation of estrogen receptor-negative MDA-MB-435 and -positive MCF-7 human breast cancer cells by palm oil tocotrienols and tamoxifen, alone and in combination. J Nutr, 1997. 127: p. 544S-548S.

3. Ikeda, S., et al., Dietary alpha-tocopherol decreases alpha-tocotrienol but not gamma-tocotrienol concentration in rats. J Nutr, 2003. 133(2): p. 428-34.

4. Khor, H.T. and T.T. Ng, Effects of administration of alpha-tocopherol and tocotrienols on serum lipids and liver HMG CoA reductase activity. Int J Food Sci Nutr, 2000. 51 Suppl: p. S3-11.

5. Shibata, A., et al., alpha-Tocopherol attenuates the cytotoxic effect of delta-tocotrienol in human colorectal adenocarcinoma cells. Biochem Biophys Res Commun, 2010.

6. Sontag, T.J. and R.S. Parker, Influence of major structural features of tocopherols and tocotrienols on their omega-oxidation by tocopherol-omega-hydroxylase. J Lipid Res, 2007. 48(5): p. 1090-8.

7. Brigelius-Flohe, R., Induction of drug metabolizing enzymes by vitamin E. J Plant Physiol, 2005. 162(7): p. 797-802.

8. Brigelius-Flohe, R., Adverse effects of vitamin E by induction of drug metabolism. Genes Nutr, 2007. 2(3): p. 249-56.

9. Fujita, K., et al., Vitamin E decreases bone mass by stimulating osteoclast fusion. Nat Med, 2012. 18(4): p. 589-94.

10. Klein, E.A., et al., Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). Jama, 2011. 306(14): p. 1549-56.

12. Muller, L., K. Theile, and V. Bohm, In vitro antioxidant activity of tocopherols and tocotrienols and comparison of vitamin E concentration and lipophilic antioxidant capacity in human plasma. Mol Nutr Food Res, 2010. 54(5): p. 731-42